Impaired blood–brain barrier function in angiotensinogen-deficient mice
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چکیده
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Impaired left-ventricular cardiac function in male GPR30-deficient mice.
G-protein-coupled receptor 30 (GPR30) has been reported to act as a membrane-bound estrogen receptor that is involved in the mediation of non-genomic estradiol signalling. In this study, we demonstrated that male, but not female, GPR30-deficient mice suffer from impaired left‑ventricular cardiac function. Left ventricles from male mutant mice were enlarged. There were no malformations in the va...
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ژورنال
عنوان ژورنال: Nature Medicine
سال: 1998
ISSN: 1078-8956,1546-170X
DOI: 10.1038/2070